Research Direction

Creating innovative therapeutic solutions from in-depth understanding of disease biology

Psoriasis


Alias: psora, white mange, ringworm, chronic eczema, sauriasis

 

Features: (1) Typical lesions clinically manifest as scaly erythematous plaques or plaques, or plaques covered with multiple layers of silvery white scales; (2) The disease may develop systemically, with the scalp, back and extremities being more common, mostly aggravated in winter; (3) A multi-system chronic inflammatory disease with a variety of comorbidities: red fever, pustules, erythrodermic-like changes and generalized large and small joint lesions may occur, and psoriatic arthritis (PsA) may occur in nearly 30% of patients with psoriasis, etc. 

 

Major Types: Common (80%-90%), Pustular, Arthritic, Erythrodermic and Psoriatic Co-morbidities

 

Based on the Guidelines for the Treatment of Psoriasis in China (2018 Complete Version), the prevalence of psoriasis in China has presented a relatively obvious trend to increase, with a prevalence of 0.123% in 1984, 0.47% in six cities in 2008, and 0.50% in four provinces in Southwest China in 2017; the prevalence of psoriasis ranges from 0.5% to 3.15% in the United States and 0.75% to 2.9% in Europe. 

 

Global epidemiological distribution of psoriasis by regions

 

Psoriasis is regarded as a chronic disabling non-communicable disease and is currently incurable, with 82% of treated patients relapsing an average of 2.6 times within 1 year. 

 

The conditions of the patients are highly visible, with 89% of them experiencing mental stress; 78% have experienced discrimination; 34% have suicidal thoughts due to psoriasis and 5% have committed suicidal acts. 

Keywords:

Psoriasis

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